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Bacterial Biofilms PDF
By:Tony Romeo
Published on 2010-11-23 by Springer

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Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

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Book which was published by Springer since 2010-11-23 have ISBNs, ISBN 13 Code is 9783642094699 and ISBN 10 Code is 3642094694

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Clinical Research in Oral Health PDF
By:William V. Giannobile,Brian A. Burt,Robert J. Genco
Published on 2009-12-09 by John Wiley & Sons

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Clinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvement.

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Manson's Tropical Diseases PDF
By:Jeremy Farrar,Peter J. Hotez,Thomas Junghanss,Gagandeep Kang,David Lalloo,Nicholas J. White
Published on 2013-12 by Saunders Limited.

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From the difficult to diagnose to the difficult to treat, Manson's Tropical Diseases prepares you to effectively handle whatever your patients may have contracted. Featuring an internationally recognized editorial team, global contributors, and expert authors, this revised and updated medical reference book provides you with the latest coverage on parasitic and infectious diseases from around the world. Incorporate the latest therapies into your practice, such as recently approved drugs and new treatment options.Find what you need easily and apply it quickly with highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams.Make the most accurate Tropical Disease diagnoses through a completely redesigned and modernized format, which includes full-color images throughout plus a wealth of additional illustrations online at Expert Consult.Apply the latest treatment strategies for HIV/AIDS, tropical neurology, malaria, and much more. Put the latest international expertise to work for you and your patients with new chapters covering Global Health; Global Health Governance and Tropical Diseases; Non-communicable Diseases; Obesity in the Tropics; and Emergency and Intensive Care Medicine in Resource-poor Settings.See which diseases are most prevalent in specific areas of the tropics through a new index of diseases by country, as well as online-only maps that provide additional detail.Better understand the variations in treatment approaches across the globe.

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Viral Infections of Humans PDF
By:Alfred S. Evans
Published on 2012-12-06 by Springer Science & Business Media

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also occurs. New outbreaks of yellow fever have occurred in Colombia and Trinidad and new outbreaks of rift valley fever have occurred in Egypt. Chapter 6, Arenaviruses: The biochemical and physical properties have now been clar ified, and they show a remarkable uniformity in the various viruses constituting the group. The possibility that prenatal infection with LCM may result in hydrocephalus and chorioretinitis has been raised. Serologic surveys have suggested the existence of Lassa virus infection in Guinea, Central African Empire, Mali, Senegal, Cameroon, and Benin, in addition to earlier identification in Nigeria, Liberia, and Sierra Leone. Chapter 7, Coronaviruses: New studies have confirmed the important role of these viruses in common respiratory illnesses of children and adults. The viruses are now known to contain a single positive strand of RNA. About 50% of corona virus infections result in clinical illness. About 5% of common colds are caused by strain DC 43 in winter. Chapter 8, Cytomegalovirus: Sections on pathogenesis of CMV in relation to organ transplantation and mononucleosis, as well as sections on the risk and features of con genital infection and disease, have been expanded. There are encouraging preliminary results with a live CMV vaccine, but the questions of viral persistence and oncogenicity require further evaluation.

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Molecular Tools and Infectious Disease Epidemiology PDF
By:Betsy Foxman
Published on 2010-12-28 by Academic Press

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Molecular Tools and Infectious Disease Epidemiology examines the opportunities and methodologic challenges in the application of modern molecular genetic and biologic techniques to infectious disease epidemiology. The application of these techniques dramatically improves the measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. This book presents the key points of consideration when integrating molecular biology and epidemiology; discusses how using molecular tools in epidemiologic research affects program design and conduct; considers the ethical concerns that arise in molecular epidemiologic studies; and provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field. The book is recommended for graduate and advanced undergraduate students studying infectious disease epidemiology and molecular epidemiology; and for the epidemiologist wishing to integrate molecular techniques into his or her studies. Presents the key points of consideration when integrating molecular biology and epidemiology Discusses how using molecular tools in epidemiologic research affects program design and conduct Considers the ethical concerns that arise in molecular epidemiologic studies Provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field

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American Journal of Mental Deficiency PDF
By:
Published on 1964 by

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Includes the association's conference proceedings and addresses.

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Social Security in America PDF
By:United States. Committee on Economic Security
Published on 1937 by

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美國眾神（影集書封版） PDF
By:尼爾‧蓋曼 Neil Gaiman
Published on 2017-04-26 by 讀書共和國出版集團／木馬文化

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引起最多討論的當代小說經典， 結合奇幻、恐怖、懸疑、公路電影等元素的類型文學， 為美國所寫的失落神話， 《雙面人魔》編劇 布萊恩富勒 + 《古戰場傳奇》Starz頻道 聯手改編當代奇幻大師尼爾‧蓋曼最經典作品， 2017年，眾神降臨！ 「神如果被人遺忘，會怎麼樣？」 「祂們會死。」 影子出獄那天，彷彿走入了另一個地獄。 深愛的妻子死了，而且與他的好友有染；他獲得了自由，但除了自由一無所有。回程路上，影子遇到一個神祕的獨眼老人。老人的名字叫星期三，聲稱自己是神，預言美國將掀起一場神的戰爭。而影子必須擔任他的保鑣，陪他橫越亞美利堅、招兵買馬。 星期三說，百年前，眾神與來自全世界的開墾者一起來到美國。當新移民在這塊大地住下，眾神也期盼在這塊土地獲得新的信徒。然而，隨著時間流逝，人們遺忘舊神、開始有了新的信仰――電視神、科技神、信用卡神。這些新神受到現代人的崇拜，一身光鮮亮麗，舊神卻越發落魄潦倒，成為邊緣「神」。祂們住在殘破的屋中，為了維生而當妓女、做工人、開計程車。當星期三來到祂們的門前，這些神或哀傷、或憤怒、或羞愧地說―― 讓我們面對事實，這塊土地根本不在意我們， 年老諸神啊，這裡是沒有神的新大陸。 新神崛起，舊神衰亡。 這就是美國，眾神墮落的地方。 尼爾蓋曼作品，2017經典重啟 《美國眾神》（American Gods）2017年5月 《蜘蛛男孩》（Anansi Boys）2017年5月（原書名：阿南西之子） 《無有鄉》（Neverwhere）2017年6月 《星塵》（Stardust）2017年6月 《好預兆》（Good Omens）2017年7月 《北歐眾神》（Norse Mythology）2017年7月 《尼爾蓋曼演說集》（The View from the Cheap Seats）2017年10月 得獎與推薦記錄 2001年美國亞馬遜網路書店年度最佳小說 2002年美國雨果獎（科幻小說獎） 2002年史托克獎（恐怖小說獎） 2002年美國軌跡獎最佳奇幻小說 2003年美國星雲獎（科幻小說獎） 2003年Geffen獎（以色列奇科幻協會文學獎）

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瘋狂亞洲富豪 II 女人有錢真好 PDF
By:關凱文 (Kevin Kwan)
Published on 2019-10-08 by 高寶書版

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比錢更重要的東西，還是錢。 比亞洲富豪更瘋狂的是……亞洲女富豪。 ★ 全球百萬暢銷書《瘋狂亞洲富豪》續集，史上含金量最高的小說，奢糜拜金、極致奢華，有錢到無法直視。 ★ 電影密集籌備中！千億富豪們強勢回歸！ ★ 女主角瑞秋的逆襲，真實背景揭曉，超強富爸爸完勝婆家。 ★ 超人氣女神艾絲翠，擺脫渣男，與舊愛再續前緣。 ★ 凱蒂・龐砍掉重練，躋身上流名媛僅差一步之遙。 不容錯過的富豪奇葩宇宙觀，超豪華私人飛機、超誇張豪宅…… 錢嘛，就是拿來花的啊。 兩年前，瑞秋被尼克的媽媽埃利諾・楊以及阿嬤嚴重羞辱，導致兩人短暫分手。兩年後的今天，兩人將在加州舉行婚禮。尼克將婚禮的細節保密到極點，徹頭徹尾瞞著埃利諾。 然而神通廣大的婆婆，在婚禮前一天搭著直升機空降會場，並帶來一個驚人的消息──其實瑞秋的生父是中國超級富豪，不僅是製藥集團老闆，更是政府高官，這讓她身價翻倍，瞬間成了埃利諾眼裡最棒的媳婦。 與拿督的兒子伯納德・戴私奔的前肥皂劇女星凱蒂・龐，即便嫁入豪門，在眾人眼裡她一樣是那個三流演員。於是凱蒂聘請一位形象顧問，從名字、外表、品味……全部砍掉重練。優雅地走入上流社交圈，是有錢人生命中最重要的事。 重磅登場的還有瑞秋同父異母弟弟的朋友柯萊特、在巴黎採購整整七天七夜的名媛們，這些人再度顛覆了瑞秋對於有錢人的想像，她們都是瘋狂亞洲富豪，不對，是瘋狂亞洲女富豪。

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Nightmare Abbey PDF
By:Thomas Love Peacock
Published on 2009-02-19 by ReadHowYouWant.com

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